This page contains the list of companies in Diagnostic Substances category. Click on the company name to get further details of the company.

Ikonisys is developing diagnostic tests for oncology and prenatal applications. Its lead product, fastFISH is a series of kits that help in identifying various prenatal conditions. FastFISH amnio is approved for identifying the chromosomal characteristics of birth defects such as Down syndrome, Edward's syndrome, and Patau syndrome. The company's oncoFish product line includes an FDA approved test for bladder cancer. The company is also developing a product can find chromosomal abnormalities in a fetus by testing the mother's blood, reducing the dangers associated with the standard, but invasive, amniocentesis procedure.

ImaRx Therapeutics, Inc. company was founded in 1999. ImaRx Therapeutics, Inc., a development-stage biopharmaceutical company, focuses on the development of therapies for stroke and other vascular disorders, using its microbubble technology. Its lead program, SonoLysis, involves the administration of its MRX-801 microspheres and ultrasound to break up blood clots and restore blood flow to oxygen deprived tissues. The MRX-801 microspheres are a proprietary formulation of a lipid shell encapsulating an inert biocompatible gas. Discontinued operations In September 2008, the company divested its urokinase business to Microbix.

Immucor, Inc. company was founded in 1982 and is based in Norcross, Georgia. Immucor, Inc., an in vitro diagnostics company, engages in the development, manufacture, and sale of reagents and automated systems. Its products are used by hospitals, reference laboratories, and donor centers to detect and identify certain properties of the cell and serum components of human blood for the purpose of blood transfusion. The company's reagent products are used in tests to identify blood group and type; to detect and identify red cell antibodies or red cell antigens; to detect and identify platelet antibodies; and to determine blood compatibility. It offers various test systems, including Capture-P, a platelet antibody detection system; Capture-R, a red cell antibody detection system; Capture-R Select, which is used for antibody screening, identification, phenotyping, cross matching, and in the weak D test; and Capture-CMV and Capture-S, which are tests for infectious diseases. Immucor, Inc. also offers automated analyzers comprising Galileo, which provides an automated solution to perform various routine blood bank tests, such as blood grouping, antibody screening, crossmatch, direct antiglobulin test, antibody identification, and cytomegalovirus and syphilis screening; Galileo Echo, a compact bench top automated instrument for the small to medium-sized hospitals, and blood banks; and Capture Workstation, a semi-automated processor, which has semi-automated components for performing capture assays manually. The company offers its medical instruments on rent. It sells its products directly in the United States, Canada, western Europe, and Japan; and through distributors internationally.

Immunomedics, Inc. company was founded in 1982 and is headquartered in Morris Plains, New Jersey. Immunomedics, Inc. (Immunomedics) is a New Jersey-based biopharmaceutical company primarily focused on the development of monoclonal, antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases. The Company has developed a number of advanced technologies that allow it to create humanized antibodies that can be used either alone in unlabeled or naked form, or conjugated with radioactive isotopes, chemotherapeutics or toxins, in each case to create targeted agents. Immunomedics has licensed its product candidate epratuzumab, to UCB S.A. (UCB), for the treatment of all autoimmune disease indications worldwide. Epratuzumab’s most advanced clinical testing is for the treatment of systemic lupus erythematosus (SLE), and in non-Hodgkin’s lymphoma (NHL). The Company has antibody product candidates in clinical development targeting B-cell NHL, other B-cell mediated diseases and various solid tumors.

Infinity Pharmaceuticals, Inc. engages in the discovery and development of medicines for the treatment of cancer and related conditions. It is conducting an international Phase III registration study of its lead product candidate, retaspimycin hydrochloride (IPI-504), an intravenously-administered small molecule inhibitor of heat shock protein 90 (Hsp90), in patients with refractory gastrointestinal stromal tumors; and a Phase I/II clinical trial in patients with advanced non-small cell lung cancer. The company's developing products include IPI-504 in combination with Taxotere in Phase Ib clinical trial for patients with solid tumors; IPI-493, an orally-delivered inhibitor of Hsp90 for patients with advanced solid tumors in Phase I clinical trial; and IPI-926, a hedgehog pathway inhibitor for patients with advanced and/or metastatic solid tumors in Phase I clinical trial. Further, the company has a discovery program focusing on fatty acid amide hydrolase, an enzyme that degrades anandamide and is targeted for neuropathic pain; and developing compounds that target Bcl-2, or Bcl-2 and Bcl-xL anti-apoptotic proteins. Infinity Pharmaceuticals has strategic alliance agreements with Mundipharma International Corporation Limited and Purdue Pharmaceutical Products L.P. to develop and commercialize pharmaceutical products; and a product development and commercialization agreement with MedImmune, Inc. to develop and commercialize cancer drugs targeting Hsp90 and the hedgehog pathway.

Innovative work in genetic testing is apparently spelled Innogenetics in any language. The biopharmaceutical company creates genetic, infectious disease, cancer, and neurological tests. Innogenetics' products include tests and genotyping profiles to identify conditions such as cystic fibrosis, HIV, hepatitis C and B, Alzheimer's disease, and human papillomavirus (HPV). In addition to testing, the company provides biological manufacturing services (producing virus strains and proteins) for pharmaceutical firms and research labs. The firm's products are sold through subsidiaries and distributors in about 90 countries. Belgium's Solvay took over control of Innogenetics in 2008.

Instrumentation Laboratory Company develops and manufactures diagnostic medical equipment primarily for hospitals and clinical laboratories around the globe. The company provides critical care systems, hemostasis products, and information management services. Its product lines include GEM and Synthesis analyzers for critical care diagnostics, and ACL and HemosIL analyzers and reagents for automated clot-timing testing. Its products are marketed through global affiliates and third-party distributors. Instrumentation Laboratory was established in 1959 and is a division of private Spanish health care company Werfen Group.

Interleukin Genetics, Inc. was founded in 1986 and is headquartered in Waltham, Massachusetts. Interleukin Genetics, Inc., together with its subsidiaries, focuses on developing, acquiring, and commercializing personalized health products that help individuals improve and maintain their health through preventive measures in the United States and internationally. It conducts, researches, develops, markets, and sells genetic test panels primarily in inflammatory and metabolic areas to provide insight into health, wellness, and disease. The company markets and distributes genetic tests under the GENSONA brand, through a strategic partnership with Alticor; and PST tests through sales and marketing partners to dentists and periodontists. It offers genetic tests for periodontal disease risk assessment, cardiovascular risk assessment, and general nutrition assessment. The company has research collaborations with the University of Sheffield, Tufts University, New York University, Harvard University, the Mayo Clinic, California Pacific Medical Center, Boston University, the University of Arkansas, Tongji Medical College, University of North Carolina, and Yonsei University.

LipoScience, Inc. company was founded in 1994 by its chief scientific officer, Dr. James Otvos. LipoScience, Inc. company's primary product, the NMR LipoProfile, uses nuclear magnetic resonance (NMR) therapy to analyze blood samples and assess the levels of lipoprotein particles in the bloodstream. (Such particles contain cholesterol, and detection of them can help pinpoint cardiovascular risks.) The LipoProfile differs from other cholesterol tests in that it does not require physical separation of the particles. LipoScience markets the LipoProfile and other traditional diagnostic tests through a direct sales force to health care providers and research labs.

lmmuCell Corporation company was founded in 1982 and is based in Portland, Maine. ImmuCell Corporation, an animal health biotechnology company, engages in the development, manufacture, and sale of products that improve animal health and productivity in the United States and internationally. It offers First Defense, an orally delivered scours preventive product that is manufactured from cows colostrums using proprietary vaccine and milk protein purification technologies. The company also provides products that aid in the management of inflammation of the mammary gland caused by bacterial infections, including Wipe Out Dairy Wipes, which consist of pre-moistened, biodegradable towelettes that are impregnated with Nisin to prepare the teat area of a cow in advance of milking; MASTiK, a mastitis antibiotic susceptibility test kit; and California Mastitis Test (CMT), which is performed at cow-side for early detection of mastitis. CMT can be used for bulk tank and individual cow sample monitoring, and for determining the quarter of the udder that is mastitic. In addition, it offers Rapid Johne's Test, which identifies cattle with symptomatic Johne's disease in a herd. Additionally, ImmuCell Corporation focuses on developing Mast Out, an intramammary infusion product containing Nisin for use in the treatment of mastitis in lactating dairy cows. It sells and markets its products primarily to veterinarians and producers in the dairy and beef industries.
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