Sinovac Biotech Ltd. is a profitable biopharmaceutical company headquartered in Beijing, China. The Company focuses on the research, development, manufacture and commercialization of vaccines that protect against human infectious diseases including hepatitis A, seasonal influenza, H5N1 (bird flu) pandemic influenza and H1N1 influenza. Sinovac received approval in 2009 for its H1N1 influenza vaccine, PANFLU.1 and has commenced fulfilling orders from the Chinese Central Government pursuit to the government stockpiling program. Sinovac was the first company worldwide to receive approval for H1N1 influenza vaccine.

MIGENIX likes to pick up compounds after they've been discovered, and shepherd them through to late-stage clinical development. After that point, the company is happy to license them out and hopefully reap the benefits. MIGENIX has partnered with Cadence Pharmaceuticals to shoulder the cost of putting its omiganan gel through Phase III clinical trials for use in preventing catheter-related infections. Cutanea Life Sciences holds the rights to develop omiganan as an acne treatment. Other clinical and pre-clinical drug candidates in the company's pipeline include potential treatments for Hepatitis B and C, blood infections, and neuro-degenerative diseases.

United Research Laboratories (URL), along with sister company Mutual Pharmaceutical (together known as URL/Mutual), manufactures generic medications and conducts research on existing drug formulas through agreements with other pharmaceutical companies. URL/Mutual has developed generic versions of drugs manufactured by King, Ortho-McNeil, Merck, and Berlex, among others. The company has also developed its own proprietary drug delivery systems. URL and Mutual Pharmaceuticals are subsidiaries of URL Pharma (formerly Pharmaceutical Holdings Corporation).

Semafore Pharmaceuticals is signaling its arrival on the oncology drug making scene. The development-stage drug discovery company is targeting the PI3K cell signaling pathways to create anti-cancer drugs. Its PI3K Inhibitors induce the death of cancerous cells in the treatment of tumors and could potentially treat brain, lung, and hematological cancers. Once administered, its lead candidate SF1126 attacks proteins expressed in tumors, but ignores healthy cells. Semafore has brought on a consulting firm to help shepherd SF1126 through its next stage of development.

Three Rivers Pharmaceuticals is looking to flow powerful drugs into the vast sea of customer affordability. The drug maker develops, manufactures, and distributes specialty pharmaceutical products for the treatment of chronic conditions, particularly viral and fungal ailments. Three Rivers Pharmaceuticals makes and markets two hepatitis C treatments in the US market: Ribasphere (a generic version of the antiviral Ribavirin) and Infergen (a branded antiviral therapy). The company also sells an injectable antifungal medication, Amphotec (also known as Amphocil), in more than 40 countries.

Human Genome Sciences, Inc. was founded in 1992 and is headquartered in Rockville, Maryland. Human Genome Sciences, Inc. operates as a biopharmaceutical company in the United States. The company's clinical development pipeline includes novel drugs to treat hepatitis C, lupus, inhalation anthrax, and cancer. It focuses on the commercialization of Albuferon (albinterferon alfa-2b) for hepatitis C and LymphoStat-B (belimumab) for lupus. The company has completed Phase III development trials for Albuferon and is conducting two Phase III clinical trials of LymphoStat-B. It also delivers doses of ABthrax (raxibacumab) to the U.S. Strategic National Stockpile for use in the event of an emergency for the treatment of inhalation anthrax. In addition, the company has various drugs in the earlier stages of clinical development for the treatment of cancer, led by the TRAIL receptor antibody HGS-ETR1 and a small-molecule antagonist of IAP (inhibitor of apoptosis) proteins. Further, Human Genome Sciences, Inc., through a strategic collaboration agreement with GlaxoSmithKline, has substantial financial rights to certain products in the GlaxoSmithKline clinical pipeline, including darapladib that is in Phase III development as a treatment for coronary heart disease; and Syncria (albiglutide), which is in Phase III development as a treatment for type 2 diabetes. Additionally, it has a strategic commercial collaboration agreement with Novartis International Pharmaceutical, Ltd. for the co-development and commercialization of Albuferon; and a strategic licensing and collaboration agreement with Aegera Therapeutics, Inc. to develop and commercialize HGS1029 and other small-molecule inhibitors of IAP (inhibitor of apoptosis) proteins in oncology.

Epigenomics AG is a Germany-based company engaged in the molecular diagnostics sector. It divides its products into two areas: solutions for early diagnosis of cancer and products for special diagnosis of cancer. Epigenomics AG produces and develops tests that help in the diagnosis of the colorectal, prostate and lung cancer. The Company also offers services in the field of identification and development of methylated deoxyribonucleic acid (DNA) biomarkers. Industry partners and the medical and life science communities can access the Company’s portfolio of filed patent families covering DNA methylation technologies and biomarkers, as well as its DNA methylation expertise through research products, biomarker services, in vitro diagnostics (IVD) development collaborations and licensing. It develops its solutions together with its commercial partners, Abbott Molecular Inc and Quest Diagnostics Inc. The Company has a subsidiary in the United States, Epigenomics, Inc.

Apex Healthcare Berhad Company makes, markets, and distributes generic pharmaceuticals and other health care products to customers in Malaysia, Singapore, Indonesia, and China. Subsidiary Xepa-Soul Pattinson (Xepa SP), the company's manufacturing arm, is Malaysia's largest generic drug maker with products including antibiotics, corticosteroids, and neuromuscular agents in tablet, capsule, liquid, cream, and powder formulations. Xepa-SP also makes nutritionals (vitamins) and surgical supplies. The company distributes its own products and those of other manufacturers to wholesale and retail customers through subsidiaries ABio, Apex Pharmacy Marketing, and Apex Pharma.

Santa Cruz, California might be known for its sun-baked bodies; Santa Cruz Biotechnology is known for its antibodies. The company makes antibodies used by researchers to identify and treat a variety of conditions. Its products include growth factor antibodies, steroid receptor antibodies, and tumor suppressor antibodies. The company also offers more than 10,000 target-specific small interfering RNA (siRNA), which are used to silence genes. Its siRNAs are designed to silence tumors suppressor proteins, cell cycle proteins, and lymphocyte signaling proteins, among others. Santa Cruz Biotechnology has offices in California, Japan, and Germany and sells its products through distributors worldwide.

Trinity Biotech plc was founded in 1992 and is headquartered in Bray, Ireland. Trinity Biotech plc develops, acquires, manufactures, distributes, and sells diagnostic test kits and instrumentation worldwide. The company offers clinical laboratory products, including diagnostic tests and instrumentation, which detect infectious diseases, sexually transmitted diseases, blood coagulation, and autoimmune disorders. It also sells raw materials to the life sciences industry. In addition, the company offers point of care diagnostic tests, which are carried out in the presence of the patient, principally to diagnose the presence of HIV antibodies in the patient. Its customers include hospitals, clinical laboratories, commercial reference laboratories, and research institutions. The company sells its products through distributor partners, as well as directly in the United States, the United Kingdom, France, and Germany.

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