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Drug Manufacturers - Major
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Drugs - Generic

Altea Therapeutics Corporation

Altea Therapeutics Corporation

Altea Therapeutics Corporation company was founded in 1998 and is based in Atlanta, Georgia. Altea Therapeutics Corporation, a pharmaceutical company, develops and commercializes transdermal patch technology that delivers therapeutic levels of water-soluble small drugs, therapeutic proteins, carbohydrates, and vaccines through the skin. It provides disease prevention products, insulin skin patches for diabetes, and acute and chronic pain management products. The company also offers PassPort Patch to deliver drugs through the skin. Altea Therapeutics Corporation was formerly known as Altea Development Corporation.

GeneThera, Inc.

GeneThera, Inc.

GeneThera, formerly called Hand Brand Distribution, develops genetic diagnostic assays for the agriculture and veterinary industries. The biotech company has developed assays that detect Chronic Wasting Disease in elk and deer, and Mad Cow Disease in cattle. The company is working on cancer detection tests for animals, as well as similar tests for humans, through its partnership with Xpention, a biotechnology company focused on oncology diagnostics. GeneThera is also developing vaccines for animal diseases, such as E. coli.

Polydex Pharmaceuticals Limited

Polydex Pharmaceuticals Limited

Polydex Pharmaceuticals likes its molecules nice and large. Polydex company produces biotech and specialty chemical ingredients for use in veterinary medicines. One of Polydex's leading products, iron dextran, is used to treat anemia in piglets. Polydex sells dextran and derivatives worldwide through subsidiaries Dextran Products and Chemdex. Taking a shot at human pharmaceuticals, the company developed a microbicidal gel for potential use as a contraceptive and prevention of sexually transmitted diseases. However, development of the product was suspended pending further investigation. Chairman, president, and CEO George Usher and his family control 47% of the voting stock of the company.

AlphaVax, Inc.

AlphaVax, Inc.

AlphaVax, Inc. company was founded in 1998 by Robert Johnston, Nancy Davis, and Jonathan Smith, AlphaVax's chief scientific officer. AlphaVax, Inc. company is developing new vaccines for cancers and infectious diseases such as HIV/AIDS, Ebola, influenza, and other viral maladies. AlphaVax relies on a proprietary alphavaccine system that genetically alters diseased cells and transforms them into a vaccine when they attempt to replicate. Its technology could be used to develop preventative vaccines and therapeutic vaccines. Its pipeline consists of early-stage candidates. AlphaVax receives funding through partnerships and grants.

Paddock Laboratories, Inc.

Paddock Laboratories, Inc.

Paddock Laboratories, Inc. company was founded in 1977 by Chairman Bruce Paddock. Paddock Laboratories, Inc. company develops and manufactures bioequivalent generic pharmaceuticals and OTC specialty products. Paddock's product line includes suppositories, diabetes treatments, topical powders, enemas, injectables, and dermatological offerings, as well as compounding bases and charcoal products. Its manufacturing facilities are located in Minneapolis, Minnesota. In addition to the US market, some of Paddock's products are sold in Europe and the Asia/Pacific region through distributors.

CombinatoRx, Incorporated

CombinatoRx, Incorporated

CombinatoRx, Incorporated company was founded in 2000 and is based in Cambridge, Massachusetts. CombinatoRx, Incorporated (CombinatoRx) is a biopharmaceutical company focused on developing synergistic combination pharmaceuticals. The Company has devoted substantially all of its resources to the development of its drug discovery technology and the research and development of its drug candidates, including conducting preclinical and clinical trials and seeking intellectual property protection for its technology and product candidates. It has been advancing a portfolio of four product candidates, Synavive (CRx-102), CRx-401, CRx-191 and CRx-197, through clinical research and development, and has a number of product candidates that have either completed Phase IIa clinical trials or are in preclinical development. Its portfolio of clinical product candidates targets multiple diseases including immuno-inflammatory diseases, metabolic disease, chronic pain and topical dermatoses. In December 2009, CombinatoRx and Neuromed Pharmaceuticals Inc. announced that they have merged.

Hi-Tech Pharmacal Co., Inc.

Hi-Tech Pharmacal Co., Inc.

Hi-Tech Pharmacal Co., Inc. was founded in 1982 and is based in Amityville, New York. Hi-Tech Pharmacal Co., Inc. (Hi-Tech) is a specialty manufacturer and marketer of prescription, over-the-counter (OTC) and nutritional products. The Company develops, manufactures and markets products in three categories: generics, prescription brands and OTC brands. It produce a range of products for various disease states, including asthma, bronchial disorders, dermatological disorders, allergies, pain, stomach, oral care, neurological disorders, glaucoma and other conditions. The Company’s generic products are primarily prescription items and include oral solutions and suspensions, topical creams and ointments, as well as nasal sprays. It also specializes in the manufacture of products in its sterile facility capable of producing liquid ophthalmic, otic and inhalation products. On February 27, 2009, the Company purchased substantially all of the assets of E. Claiborne Robins Company, Inc. doing business as, ECR Pharmaceuticals (ECR Pharmaceuticals or ECR).

Xceed Molecular

Xceed Molecular

Xceed Molecular is working to exceed the expectations of researchers performing gene expression tests. The company's flow-thru chip technology allows biotechnology and pharmaceutical companies to conduct genetic screening research. Its Ziplex system is used for automated gene expression analysis. Other products include assay reagent kits, sample preparation reagents, and its TipChip disposable microarrays. The company also produces chips to detect specific diseases and is working to speed up the time needed to process samples. Xceed Molecular, which was established in 2001, has facilities in Canada and the US.

CytoGenix, Inc.

CytoGenix, Inc.

CytoGenix, Inc. company was founded in 1995 and is based in Houston, Texas. CytoGenix, Inc. operates as a biopharmaceutical company. It focuses on the development and commercialization of its proprietary technologies for identifying and silencing disease causing genes; and expressing proteins for applications, such as vaccines and isolating novel nucleic acid-based anti-microbial compounds. The company’s technologies include gene silencing techniques (ssDNA) applicable to genes from pathogenic organisms or selected genes from a patient to prevent the expression of harmful proteins; a novel, cell free process to produce large quantities of DNA (synDNA) for use in its own products and for sale to other biopharmaceutical or life science companies; and a methodology to isolate and characterize novel DNA-based drugs (Oligogenix) to which harmful bacteria have not developed resistance. Its products under development include SIMPLIVIR, an anti-herpes topical compound; Oligogenix technique based compounds against methicillin and vancomycin resistant staphylococcus aureus; and DNA vaccines for use in humans, poultry, aquaculture, and cattle. The company in collaboration with the United States Department of Agriculture, engages in a project to develop a synDNA based vaccine against brucellosis, a zoonotic disease which is easily transmitted from animals to humans.

Kalypsys, Inc.

Kalypsys, Inc.

Kalypsys is searching for new medicines, and has developed a zippy way to find them. Its ultra-high throughput automated epiK screening system can analyze more than one million cell-based assay wells a day and can run 24 hours a day seven days a week. With that kind of research capability, the company has developed its own bioinformatics software to enable researchers to quickly find and compare data points. Kalypsys is generous enough to market the system, under the Kalypsys Systems brand, to other pharmaceutical research facilities. Its own drug development pipeline includes compounds in early stages of development, targeting cancer, inflammatory diseases, pain, and metabolic diseases.

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