Laboratorios Farmacéuticos ROVI manufactures and sells pharmaceuticals in Spain and the rest of Europe. Its best selling prescription drugs include Hibor, (a brand name heparin used to prevent blood clots during surgery), osteoporosis drug Osseor, and angina drug Corlentor. ROVI's handful of OTC products include Autan insect repellant and the Enerzona line of dietary wellness products.In 2009 the company licensed Novavax's VLP vaccine technology which it will use to create a flu vaccine for the Spanish government. The E60 million ($84 million) program is being sponsored by the Spanish Ministry of Health. ROVI was founded in 1946 and went public on the Spanish Stock Exchange in late 2007.

Titan Pharmaceuticals thinks big. The development-stage firm is working on drug treatments for large pharmaceutical markets, including central nervous system disorders like chronic pain, Parkinson's disease, and schizophrenia. On its own, the company is developing Probuphine, which may treat opioid addiction; Probuphine combines an already-approved chemical compound with Titan's continuous-release drug delivery technology called ProNeura. Titan is working with Vanda Pharmaceuticals on late-stage compound Iloperidone, a possible treatment for schizophrenia.

Minster Pharmaceuticals plc, through its subsidiary, Minster Research Limited, develops pharmaceutical compounds for the treatment of neurological and psychiatric conditions in the United Kingdom. Its products pipeline comprises Tonabersat, which is in Phase IIb clinical trial for the prevention and treatment of migraine; and Sabcomeline, a Phase IIa clinical trial product for the management of cognitive decline and negative symptoms in schizophrenia. The company is based in Saffron Walden, the United Kingdom.

Stiefel Laboratories, Inc. company's products treat a variety of dermatological ailments including acne, psoriasis, and even warts. Among the company's prescribed products are Duac and Brevoxyl acne medications and rosacea treatment Rosac. Stiefel also makes such over-the-counter remedies as fungal infection treatment Zeasorb and Sarna Lotion for itchy skin. Through subsidiaries, the company has manufacturing, marketing, and research operations in more than 30 countries, and markets it products in more than 70 countries. Founded in 1847, the company was owned by the Stiefel family before being acquired by GlaxoSmithKline in 2009.

Alacer Corp. will "C" you through your cold. Maker of the popular Emergen-C fizzy drink mix, the company set the cornerstone on branded vitamin C products. In addition to Emergen-C, which blends mineral ascorbates with B vitamins and mineral complexes, the company's other products include ElectroMIX (electrolyte drink mix) and its Super Gram time-released tablets. Alacer also develops other vitamin and herbal supplements, all with a walloping dose of vitamin C stirred in. Its products are sold through natural foods retailers, mass market retailers, and chain drug stores.

Beijing Tongrentang Co., Ltd. company makes and sells a variety of traditional Chinese herbal medicines under the Tongrentang brand. Products include treatments for a number of maladies including colds and fevers, and preparations designed to improve circulation and kidney function. Tongrentang also exports its herbal remedies and has expanded beyond Chinese borders through a number of joint ventures and subsidiaries, establishing retail drug stores and clinics specializing in traditional Chinese medicine. The company's origins date back more than 300 years as a family business offering its remedies in Beijing during the Qing Dynasty.

Discovery Laboratories was founded in 1992 and is headquartered in Warrington, Pennsylvania. Discovery Laboratories, Inc., a biotechnology company, engages in developing surfactant replacement therapies (SRT) to treat respiratory disorders and diseases. The company's proprietary technology, KL4 Surfactant Technology, produces a synthetic, peptide-containing surfactant that is structurally similar to pulmonary surfactant. Its products include Surfaxin, a synthetic, peptide-containing surfactant for use in pediatric medicine; Surfaxin (lucinactant) for the prevention of respiratory distress syndrome (RDS) in premature infants; and Aerosurf, which is a KL4 Surfactant in aerosolized form to treat premature infants at risk for RDS. Discovery Laboratories also focuses on the development of Surfaxin to address bronchopulmonary dysplasia in premature infants, acute respiratory failure in children, cystic fibrosis, acute lung injury, and other diseases associated with the inflammation of the lung, such as asthma and chronic obstructive pulmonary disease. The company has a license agreement with Philip Morris USA Inc. to use its Capillary Aerosolization Technology for use with pulmonary surfactants for the respiratory diseases; and has a strategic alliance with Laboratorios del Dr. Esteve, S.A. to develop, market, and sell surfactant products in Andorra, Greece, Italy, Portugal, and Spain.

IntelliPharmaCeutics International (IPC) is getting smarter about drug delivery by the second. The pharmaceutical company uses its controlled release drug delivery technology to develop new and generic drug products for enhanced treatment of pain, cardiovascular, and neurological issues. Its products are based on its patented HYPERMATRIX platform, which controls a drug's release time within the gastrointestinal tract. With a diverse pipeline, IPC develops its own proprietary products, as well as ones for third parties, including international clients; it also offers contract manufacturing. In 2009 the formerly private company merged with Vasogen to create the publicly traded IntelliPharmaCeutics International.

Ash Stevens, Inc. was founded in 1962 to provide chemical research for the government and later branched out into the private sector. Ash Stevens, Inc. company, a contract pharmaceutical manufacturer develops and manufactures active pharmaceutical ingredients (APIs) for other pharmaceutical companies. It also supports clinical drug trials and helps others navigate the FDA's regulatory maze. Its customers include the federal government and commercial pharmaceutical firms. The company's portfolio includes about a dozen FDA-approved drug components.

Metagenics, Inc., doing business as Ethical Nutrients, manufactures and distributes medical foods and nutraceuticals to healthcare practitioners. The company offers FirstLine Therapy programs for the prevention and management of chronic conditions, including diabetes, cardiovascular disease, and arthritis. It distributes its products in North America, South America, Europe, and Asia. The company was founded in 1983 and is headquartered in San Clemente, California with research and development centers in Gig Harbor, Washington; and Ithaca, New York. It has manufacturing facilities in Gig Harbor, Washington. As of September 11, 2009, Metagenics, Inc. operates as a subsidiary of Alticor Inc.

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