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Biotechnology
Diagnostic Substances
Drug Delivery
Drug Manufacturers - Major
Drug Manufacturers - Other
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Drugs - Generic

Alimera Sciences, Inc.

Alimera Sciences, Inc.

Alimera Sciences' tunnel vision is a real asset. The biopharmaceutical company specializes in prescription ophthalmic pharmaceuticals, particularly those aimed at treating ocular diseases affecting the retina. Alimera's most advanced product candidate, Iluvien, is an insert about the size of a grain of rice that slowly releases a drug to the back of the eye used in the treatment of diabetic macular edema (DME); DME, a retinal disease affecting diabetics, can lead to severe vision loss and blindness. Iluvien is effective for up to 36 months and may also have the potential to affect other ophthalmic diseases, such as retinal vein occlusion (RVO). Alimera Sciences is looking to go public through an $80 million IPO.

BioTime, Inc.

BioTime, Inc.

BioTime, Inc. company was founded in 1990 and is headquartered in Alameda, California. BioTime, Inc. is a biomedical organization engaged in the development of synthetic plasma expanders and blood volume substitute solutions for use in surgery, trauma care, organ transplant procedures, and other areas of medicine. The Company’s operating revenues have been generated primarily from licensing fees related to the sale of its plasma volume expander products, primarily Hextend. The company began to make its first stem cell research products available during the year ended December 31, 2008, but it had not yet generated significant revenues in that business segment.

Shionogi Pharma, Inc.

Shionogi Pharma, Inc.

Shionogi Pharma, Inc. company was founded in 1992 and is headquartered in Atlanta, Georgia. Sciele Pharma Inc. operates as a subsidiary of Shionogi & Co. Ltd. Sciele Pharma Inc., a pharmaceutical company, engages in acquiring, developing, marketing, and selling prescription products for patients primarily in the United States. It offers oral suspensions, tablets, and capsules, as well as products prescribed by the primary care physicians. The company provides cardiovascular and diabetes products that treat patients with high cholesterol, hypertension, high triglycerides, unstable angina, and Type 2 diabetes; pediatrics products, which treat allergies, asthma, cough and cold, and attention deficit and hyperactivity disorders; and products for the health and well-being of women, as well as for mothers and their babies. It develops glycopyrrolate oral solution, a treatment for chronic, moderate-to-severe drooling in pediatric patients.

Novo Nordisk A/S

Novo Nordisk A/S

Novo Nordisk A/S was founded in 1925 and is headquartered in Bagsvaerd, Denmark. Novo Nordisk A/S, a healthcare company, engages in the discovery, development, manufacture, and marketing of pharmaceutical products. It operates in two segments, Diabetes Care and Biopharmaceuticals. The Diabetes Care segment covers insulin franchise, including modern insulins, human insulins, insulin-related sales, and oral antidiabetic drugs, as well as GLP-1 compounds in development for both the treatment of type 2 diabetes and as an anti-obesity agent. The Biopharmaceuticals segment provides products in the areas of haemostasis management, growth hormone therapy, hormone replacement therapy, inflammation therapy, and other therapy areas. The company sells its products principally in the United States, Japan, China, the Russian Federation, India, Turkey, and other European countries.

Grifols, S.A.

Grifols, S.A.

Grifols' focus is on producing plasma derivatives (plasma proteins for therapeutic use). This business generates about 70% of the group's annual revenue. Its diagnostic division manufactures devices, instrumentation, and reagents for clinical analysis labs, and markets products and equipment for blood banks. The third line of business, the hospital division, develops pharmaceutical products and medical devices used in hospital pharmacies. Clients include health care professionals and patients in more than 90 countries. Nearly three-quarters of Grifols' total sales come from international markets.

Ceragenix Pharmaceuticals, Inc.

Ceragenix Pharmaceuticals, Inc.

Ceragenix Pharmaceuticals was founded in 2002 is based in Denver, Colorado. Ceragenix Pharmaceuticals, Inc. operates as a medical device company focusing on infectious diseases and dermatology in the United States. The company has two base technology platforms, which include Ceragenins for the treatment of infectious disease; and Barrier Repair for the treatment of dermatological disorders, including atopic dermatitis, neonatal skin disorders, and others. Its Ceragenin compounds are active against a range of gram positive and negative bacteria. The company uses its Ceragenin technology to formulate Cerashield antimicrobial coatings for medical devices. Its Barrier Repair technology is the platform for the development of two prescription topical creams, including EpiCeram, a prescription product for the treatment of dry skin conditions and to manage and relieve the burning and itching associated with various types of dermatoses, including eczema, irritant contact dermatitis, and radiation dermatitis; and NeoCeram, a pediatric barrier repair cream intended to create a skin barrier in premature infants and neonates.

DOV Pharmaceutical, Inc.

DOV Pharmaceutical, Inc.

DOV Pharmaceutical, Inc. is a biopharmaceutical company focused on the development of product candidates for disorders of the central nervous system (CNS). The Company has drug development programs that are at the preclinical, Phase I and Phase II clinical stages, including DOV 21,947 (in a Phase II clinical trial for depression), DOV 102,677 (which has completed a Phase I clinical trial) and a preclinical discovery program in reuptake inhibitors and GABA modulators. The Company also has a drug development program subject to regulatory review, Indiplon, which is being developed as a treatment for insomnia. The Company has sublicensing agreements for the development and commercialization of certain product candidates with XTL Biopharmaceuticals, Inc. (XTL) for bicifadine, with Blue Note Pharmaceuticals, Inc. (Blue Note) for DOV diltiazem, and with Neurocrine Biosciences, Inc. (Neurocrine) for indiplon.

LipoScience, Inc.

LipoScience, Inc.

LipoScience, Inc. company was founded in 1994 by its chief scientific officer, Dr. James Otvos. LipoScience, Inc. company's primary product, the NMR LipoProfile, uses nuclear magnetic resonance (NMR) therapy to analyze blood samples and assess the levels of lipoprotein particles in the bloodstream. (Such particles contain cholesterol, and detection of them can help pinpoint cardiovascular risks.) The LipoProfile differs from other cholesterol tests in that it does not require physical separation of the particles. LipoScience markets the LipoProfile and other traditional diagnostic tests through a direct sales force to health care providers and research labs.

BioDelivery Sciences International, Inc.

BioDelivery Sciences International, Inc.

BioDelivery Sciences International, Inc. company was founded in 1997 and is based in Raleigh, North Carolina. BioDelivery Sciences International, Inc. operates as a specialty pharmaceutical company in the United States. Its patented drug delivery technologies include BEMA drug delivery technology and Bioral cochleate drug delivery technology. The company, using its drug delivery technologies, develops formulations of pharmaceuticals aimed principally at short term acute conditions occurring in patients, primarily in the areas of pain and fungal infections. Its lead product is ONSOLIS, a treatment for pain in opioid tolerant patients with cancer. BioDelivery Sciences licensed the commercialization and distribution rights for ONSOLIS to Meda AB.BioDelivery Sciences Company's products/formulations also include BEMA Buprenorphine, which is under preparation for phase 2 for moderate to severe and acute pain. Its lead Bioral formulation is an encochleated version of Amphotericin B, an anti-fungal treatment for systemic fungal infections. The company also has a Bioral formulation, which is in initial in vitro studies for the intranasal administration of Amphotericin B to treat chronic rhinosinusitis. BioDelivery Sciences has a research collaboration and licensing agreement with the Drugs for Neglected Diseases initiative (DNDi) to develop Bioral Amphotericin B for the treatment of neglected diseases, such as leishmaniasis and Chagas disease.

GE Healthcare Medical Diagnostics

GE Healthcare Medical Diagnostics

GE Healthcare Medical Diagnostics helps your doctor to see right through you. The division, formerly Amersham plc, is one of the world's top producers of contrast-imaging agents and nuclear medicine agents used to enhance image quality in X-ray, magnetic resonance imaging, and ultrasound procedures. General Electric formed the division when it acquired Amersham and placed under its GE Healthcare umbrella. The former Amersham bioscience operations, which makes purification systems that allow for the development of more effective drugs through protein analysis, DNA sequencing, and genetic variation, is part of the GE Healthcare Life Sciences division.

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