Galapagos has formed its own archipelago of drugs to treat bone and joint ailments and other diseases. The company uses its proprietary genomic drug-discovery technology to develop medicines to treat rheumatoid arthritis, osteoarthritis, and osteoporosis. Galapagos' pharma services subsidiaryBioFocus DPI offers collaborative drug-discovery services to other pharmaceutical companies. Its drug discovery division works with partners to find, test, and market new drugs. The company's pharmaceutical collaborators include top drugmakers GlaxoSmithKline, Eli Lilly, Merck, and Janssen Pharmaceutica, part of Johnson & Johnson. Galapagos has about 40 projects in its R&D pipeline, most of them through these partnerships.

Synteract, Inc. company has overseen hundreds of projects for clients that include biotechnology and pharmaceutical companies, as well as medical device makers. On top of research services, Synteract offers clients proprietary and customizable software solutions for managing research and trial data. The company's expertise covers a wide range of health issues, including oncology, HIV/AIDS, ophthalmology, and gastrointestinal disorders. Founded in 1995, Synteract maintains offices in San Diego, Philadelphia, and North Carolina.

Ranbaxy Pharmaceuticals Inc. company, the US arm of Indian generic pharmaceuticals giant Ranbaxy Laboratories Limited, makes and markets about 50 generic and over-the-counter (OTC) drugs. It accounts for about a quarter of its parent's annual revenues. RPI's generic offerings, produced by manufacturing subsidiary Ohm Laboratories, include anti-infectives and treatments for cardiovascular, gastrointestinal, and central nervous system disorders. Its OTC products include analgesics, antihistamines, and decongestants. Sister subsidiary Ranbaxy Laboratories, Inc. (RLI) develops branded pharmaceuticals.

PRA International knows it takes more than laboratory research to get drugs approved. The company, a clinical research organization (CRO), provides an array of drug development services to pharmaceutical and biotech companies around the world. Services the company offers include clinical trials management, database development, and regulatory filings preparation. PRA's clients are engaged in most major therapeutic areas, but the firm's particular strengths lie in oncology, central nervous system disorders, cardiovascular disease, allergy and respiratory disorders, and infectious disease. The company is owned by private equity firm Genstar Capital.

Theratechnologies is pepped up on peptides. The Canadian company develops peptide sequences to treat endocrine and metabolic conditions such as growth hormone deficiencies. Lead drug candidate tesamorelin is a growth hormone-releasing peptide that Theratechnologies believes can combat a variety of problems, including HIV-related lipodystrophy (the metabolic syndrome characterized by changes in distribution of adipose tissue), muscle wasting associated with chronic obstructive pulmonary disease, sleep maintenance insomnia, and immune dysfunction in elderly patients.

Neogen Corporation was founded in 1981 and is based in Lansing, Michigan. Neogen Corporation (Neogen), together with its subsidiaries, develops, manufactures and markets a line of products dedicated to food and animal safety. The Company operates in two primary business areas: the food safety segment and the animal safety segment. The Company’s food safety segment consists primarily of diagnostic test kits and complementary products marketed by sales personnel in the North American, Mexico, the United Kingdom and other parts of Europe, and by distributors elsewhere to food producers and processors to detect dangerous and/or unintended substances in human food and animal feed. Neogen’s animal safety segment is engaged in the development, manufacture and marketing of pharmaceuticals, rodenticides, disinfectants, vaccines, veterinary instruments, topicals and diagnostic products for the worldwide animal safety market. In May 4, 2009, Neogen acquired International Diagnostic Systems Corporation.

Life sciences researchers go shopping for molecules at Research and Diagnostic Systems The company (aka R&D Systems) is the primary subsidiary of TECHNE and manufactures and sells the tools used in life sciences research. Its biotechnology division offers thousands of proteins, antibodies, stem cells, and other handy stuff for researchers. Its BiosPacific subsidiary supplies biological ingredients to makers of in vitro diagnostic kits. R&D Systems' hematology division sells the blood components and equipment used to calibrate blood analysis equipment. Clients include pharmaceutical and biotechnology companies and academic and institutional research facilities.

TargeGen is developing small molecule therapeutics to treat cancer and cardiovascular disease. The development-stage firm's lead drug candidate, TG 100-115, could prevent complications after heart attacks. Other therapies in TargeGen's pipeline include a potential treatment for colorectal cancer, non-small cell lung cancer, and macular degeneration, an eye condition that often leads to blindness. The biotech company had been eying an IPO but opted in mid-2005 to stay private and took on an additional round of venture capital financing to fund trials of TG 100-115.

Established in 1989 as the commercial arm of the Scottish Crop Research Institute, MRS assists UK agricultural and plant biotechology scientists develop their ideas into marketable products. Profits earned from its efforts are plowed back into the research institution. MRS labs offer pathogen testing, plant analysis, and consulting services. MRS works with companies interested in licensing technologies that the researchers use to breed high-quality varieties of potatoes, soft fruits, barley, and other agricultural products.

Amarin Corporation plc (Amarin) is a late-stage biopharmaceutical company with a focus on cardiovascular disease. Amarin has a range of clinical and preclinical stage compounds to treat central nervous system (CNS) disorders, including Huntington’s disease, myasthenia gravis and Parkinson’s disease. Its cardiovascular programs and non-core CNS programs include AMR101, EN101, Sublingual Apomorphine and AMR 103. The Company's subsidiaries include Amarin Neuroscience Limited, Amarin Pharmaceuticals Ireland Limited, Amarin Pharma Inc, Amarin Finance Limited and Ester Neurosciences Limited.

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