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Accellent provides the nuts and bolts for the medical device industry. The company offers outsourced design, engineering, and manufacturing of custom components, subassemblies, and completed devices, primarily for medical device firms. Its customers include such industry leaders as Medtronic, Abbott Labs, Stryker, and Johnson & Johnson. Accellent specializes in equipment used for cardiac rhythm management, interventional cardiology, neurology, and orthopedics, as well as urology and minimally invasive procedures (especially in the field of endoscopy). It also offers its customers complete supply chain management. The company owns or leases about 25 locations in North America and Europe.

Acclarent's medical technology helps people breathe easy without surgery. The company created the Balloon Sinuplasty, a minimally-invasive device used to treat patients with chronic sinusitis. The Balloon Sinuplasty opens blocked sinuses by inflating a balloon in the sinus cavity instead of cutting away bone and tissue, and patients can return to work as soon as the next day. The FDA-approved device is marketed directly to ear, nose, and throat (ENT) doctors in the US and internationally. Acclarent was acquired by Ethicon, a Johnson & Johnson subsidiary and a leading maker of medical equipment, in 2010.

Accuray's CyberKnife radiosurgery system zaps solid tumors with precisely aimed, high-dose radiation. The system, approved for use in the US, the EU, and several Asian countries, improves upon older radiosurgery systems that have limited mobility and are mostly used to treat brain tumors. Doctors can use CyberKnife to treat tumors anywhere in the body; the system tracks and adjusts for movement in real time, allowing for patient and tumor movement. Procedures with CyberKnife require no anesthesia and can be performed on an outpatient basis. Roughly 200 of the systems have been installed in hospitals around the world, more than 65% of them in the US.

ACI Medical helps your blood go with the flow. The company manufactures and markets pneumatic compression devices used to increase blood flow for patients with severe vascular conditions. Products include: ArtAssist, which increases arterial blood flow in the legs using compression; VenaPulse, which creates pressure to a patient's limbs during vascular testing; and VenAssist, which works to prevent deep vein thrombosis (clots). Its APG device is a diagnostic tool designed to evaluate the type and severity of vascular conditions a patient may have. The company also manufactures miniature pumps and does custom injection molding. ACI Medical was founded in 1984.

No, the Six Million Dollar Man isn't working at hearing technology firm Advanced Bionics. The company has the technology not to make a person "better, faster, and stronger," but instead to help people with severe to profound hearing loss to hear. A leading provider of cochlear hearing devices, Advanced Bionics makes the Harmony HiResolution Bionic Ear System, which includes a cochlear implant, sound processor, and other equipment that together can restore hearing to the deaf. The company provides mentoring and support services to implant customers worldwide. Advanced Bionics was acquired by global hearing aid manufacturer Sonova for $489 million in early 2010.

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