Orthofix International N.V. makes a variety of spinal and orthopedic devices and sports medicine products used to immobilize and patch bone, as well as stimulate new growth. Its products include Firebird spinal fixation systems, Spinal-Stim bone growth stimulator, TRUE/LOK ring fixation systems for limbs, BREG Bracing limb support, and Trinity Evolution, a stem-cell based bone grafting material. The company also produces a system to improve blood flow in immobilized patients. Orthofix sells its products to healthcare providers through subsidiaries and independent distributors in Brazil, Europe, Mexico, and the US.

Advocate Health Care is a not-for-profit, integrated health care network with more than 200 sites serving the Chicago and surrounding areas. Advocate's operations include about a dozen acute and specialty care hospitals (including Christ Medical Center, Hope Children's Hospital, and Lutheran General Hospital) with more than 3,400 beds, as well as community health clinics and home health care and hospice services. The health system includes the largest physician network of primary care physicians, specialists, and sub-specialists in the state. Advocate Health acquired BroMenn Healthcare System in 2010.

Flex Partners will bend over backwards to help bring a new medical device to market. The engineering firm provides established and start-up medical device firms with a host of design and development services, from prototyping to business development. The company has more than 20 patents on disposable and reusable devices used for urological, cardiovascular, orthopedic, oral and plastic surgical procedures. Other services include market research, competitor intelligence, brand creation, and executive recruitment. Flex Partners was founded in 1980.

Sage Products knows that when it comes to warding off disease and infection, it pays to be wise. Sage Products company manufactures and distributes a variety of hygiene products for bathing, incontinence, and oral care. It also makes gloves, gowns, warmers for its cleansing cloths, and industrial microwaves. Sage sells its products worldwide to health care providers, consumers, and the military through supply contracts and through its consumer-products Web site. Many Sage products are water-free, including prepackaged bathing cloths and preoperative skin preparation cloths, making them particularly useful for troops in the field. Sage was founded in 1971 by CEO Vincent Foglia and director Paul Hills.

Freeman Health System offers comprehensive health and behavioral health to the residents of Arkansas, Kansas, Missouri, and Oklahoma through three hospitals with a total of more than 400 beds. Specialty facilities include a full-service cardiothoracic and vascular program at the Freeman Heart Institute, and behavioral health services through its Ozark Health Center. The community-owned Freeman system also operates two urgent care centers, a separate sleep center, several doctors' office buildings, and serves as a teaching hospital with three residency programs (ear, nose, and throat; emergency medicine; and internal medicine).

Riverview Hospital provides general medical and surgical care to residents in Hamilton County, just north of Indianapolis in central Indiana. With about 150 beds, the hospital is a full-service facility and offers specialty care in a number of areas, including heart disease, cancer, women's health, and orthopedics. In addition to its main campus, Riverview operates several outpatient facilities, including an occupational health center, a community health clinic, and several rehab and fitness centers. Its Riverview Medical Group is a network of affiliated primary and specialty care doctors with offices located throughout the hospital's service area.

Columbia St. Mary's serves Southeastern Wisconsin (Milwaukee, Ozaukee, and Washington counties) through a health care network that includes four hospitals -- Columbia St. Mary's Milwaukee Campus, Columbia St. Mary's Ozaukee Campus, Columbia St. Mary's Columbia Campus, and the Sacred Heart Rehabilitation Institute. Other members of the health system include about 50 community clinics, the Columbia College of Nursing, the River Woods Outpatient Center and the Cathedral Square Urgent Care Center. The Catholic Sisters of Charity founded St. Mary's Hospital in Milwaukee in 1848 at the request of Bishop John Martin Henni. The company is sponsored by Ascension Health and Columbia Health System.

Silver Cross Hospital admitted its first patient in Joliet, Illinois, in 1895. Silver Cross Hospital and Medical Centers has grown to serve the Illinois counties of Will, Grundy, and Cook through its main hospital campus (with more than 300 beds) and several satellite facilities throughout the area. Its services include cardiovascular care, women's health, rehabilitation, and behavioral health care. Outpatient facilities provide primary and specialty care services, including medical imaging and dialysis. The hospital's name comes from the emblem (the Maltese Cross) of the Christian organization that founded the not-for-profit hospital, the International Order of The King's Daughters and Sons.

Henrico Doctors' Hospital comprises a network of hospital campuses -- Forest, Parham, and Retreat -- that serve central Virginia through its respective Richmond locations. With a total of more than 760 beds, the acute care hospital group provides a range of emergency, medical, surgical, and rehabilitative services, with specialties in cardiac care, oncology, orthopedics, women's health, diagnostic imaging, and minimally invasive robotic surgery (a system designed to improve upon the traditional laparoscopy). It is also a national leader in kidney transplants and a leader in stroke care in Virginia. Henrico Doctors' Hospital is part of the HCA Virginia Health System, itself a subsidiary of US hospital operator HCA.

MidState Medical Center isn't lost in the middle. The acute care hospital serves central Connecticut and has some 145 beds (including six psychiatric beds). It offers patients a range of services including cardiac, emergency medicine, and maternity care. MidState Medical Center also has centers dedicated to diabetes, cancer treatment, digestive health, nutrition, and women's health. The hospital has been working hard to keep up with increasing demand for its services. It has built an addition to its campus that added emergency medical care services as well as opened a MidState Medical Services Building, to increase its outpatient care capacity.

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