UC Irvine Medical Center is the only Level I trauma center in Orange County. It also offers acute- and general-care services from about 400 specialty and primary care physicians. The medical center operates one of four cancer centers in California (its Chao Family Comprehensive Cancer Center) and outpatient clinics throughout the region. The UC Irvine Medical also boasts neuropsychiatric and regional burn centers. Together UC Irvine Medical and University Physicians & Surgeons -- a faculty practice organization -- comprise UC Irvine Healthcare.

No, the Six Million Dollar Man isn't working at hearing technology firm Advanced Bionics. The company has the technology not to make a person "better, faster, and stronger," but instead to help people with severe to profound hearing loss to hear. A leading provider of cochlear hearing devices, Advanced Bionics makes the Harmony HiResolution Bionic Ear System, which includes a cochlear implant, sound processor, and other equipment that together can restore hearing to the deaf. The company provides mentoring and support services to implant customers worldwide. Advanced Bionics was acquired by global hearing aid manufacturer Sonova for $489 million in early 2010.

Universal Health Services, Inc. owns or leases about two dozen acute care hospitals with more than 6,000 total beds, as well as seven outpatient surgery centers, radiation therapy centers, and surgical hospitals. In addition to these medical facilities, UHS runs about 200 psychiatric and substance abuse hospitals. The company's facilities are located mainly in smaller towns and cities with limited competition, but it does have operations in some larger markets, including Las Vegas, Memphis, and Austin, Texas.

The development-stage medical device company,EnteroMedics Inc. uses neuroblocking technology called VBLOC therapy to combat obesity. Its initial product in development, the Maestro System, is a device laparoscopically implanted near the diaphragm that uses electrical impulses to limit the expansion of the stomach, thereby producing a feeling of prolonged fullness. The Maestro System is in US and international clinical trials, with FDA approval and commercial sales anticipated by 2010. EnteroMedics plans to build a direct sales force to market the product to bariatric surgeons and weight management specialists.

Baystate Health is the largest health care services provider in western Massachusetts. The system operates four acute-care hospitals with a total of more than 780 beds, and a specialized children's hospital with nearly 60 bassinettes. Baystate Health offers ancillary medical services, including cancer care, respiratory care, infusion therapy, visiting nurse, and hospice services. The system holds a majority of Health New England, a for-profit HMO with more than 100,000 members in western Massachusetts. Baystate Health is the only Level 1 Trauma Center and teaching hospital in the region.

DaVita Inc. provides dialysis services for patients suffering from chronic kidney failure, which is known as end stage renal disease (ESRD) in the United States. The company operates kidney dialysis centers, and provides related medical services primarily in dialysis centers and in contracted hospitals. Its services include outpatient dialysis services; hospital inpatient hemodialysis services; and ESRD laboratory services. The company also offers infusion therapy services; DaVita Rx, a pharmacy that provides oral medications to patients with ESRD; vascular access services; disease management services and special needs plans; physician services; and clinical research programs.

Formed in 1996, the company operates through about 20 branches located throughout the US. Just because a ventilator has a few scratches and dents doesn't mean it's headed for the junkyard. Not with Freedom Medical around anyway. Freedom Medical refurbishes capital medical equipment (dialysis machines, ventilators, patient monitors, and the like) and then sells or rents it to cash-strapped hospitals, alternate care sites, ambulance companies, and medical equipment dealers. It also provides repair and maintenance services.

Covance, with headquarters in Princeton, New Jersey, is one of the world’s largest and most comprehensive drug development services companies, with annual revenues greater than $1.8 billion, employees in more than 60 countries, and more than 10,000 employees worldwide The drug development industry has come along way in the last two decades. In the 1980s and early 1990s, when the focus was on cost-savings and capacity management, contract research organizations (CROs) were used primarily as spillover capacity. The work was done and often done well, but our relationship with our pharmaceutical clients was tactical, and CRO growth rates and profitability were volatile. From roughly 2000 to 2005, biotechnology and specialty pharmaceutical companies began to use CROs more strategically, which stabilized demand and improved the performance and return on investment of CROs.

BSD Medical has developed equipment to provide hyperthermia treatment, specifically for treating cancer (including melanoma, breast cancer, brain cancer, and cervical cancer) in tandem with chemotherapy and radiation therapy or as a stand-alone treatment. BSD Medical was the first to develop an approvable hyperthermia system, which uses focused radio frequencies and microwaves to heat cancer cells until they die. The company's devices are designed to target superficial tumors, as well as tumors located deep within a patient's body. Its products are sold to clinics, hospitals, and other cancer-treatment institutions through its sales force and external distributors.

ValleyCare Health System is a not-for-profit health care organization serving Livermore and Pleasanton, California and the surrounding areas east of San Francisco. ValleyCare Health System consists of two medical campuses and a number of hospitals that offer acute and general health care services, with a total of more than 200 beds and a medical staff of 300-plus. The system also includes specialty outpatient clinics providing behavioral health, outpatient surgery, occupational health and rehabilitation, and wellness services. ValleyCare Health System also operates a senior housing facility.

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