Unity Health System brings together a host of health care services for the good people of Rochester, New York, and western Monroe County. The 680-bed system's main facility is Unity Hospital (what was Park Ridge Hospital until 2006). Its Unity St. Mary's Campus (formerly St. Mary's Hospital) offers a variety of community-based health care services, such as primary care clinics, dental offices, and urgent care services, as well as specialized psychiatric, rehabilitative, and cancer care, among other things. Unity St. Mary's also operates a nursing home and a senior living facility (known as Moore Park Apartments).

Health Plan of Nevada, a subsidiary of UnitedHealth, is a Nevada health maintenance organization (HMO) offering health care coverage to the state's residents. Its offerings include various HMO and point-of-service (POS) plans, as well as prescription drug coverage. It also gives members access to its affiliated multi-specialty medical group, Southwest Medical Associates, and other health care and wellness services. Established in 1982, Health Plan of Nevada offers plans through employer groups as well as to individuals. It sells its Senior Dimensions HMO plans to Medicare beneficiaries.

Paradigm Management doesn't want complex worker's compensation cases to get out of hand. Paradigm Management company maintains a network of medical specialists, nurse case managers, and physicians that oversees cases of catastrophic injuries and complex medical conditions, such as amputations, burns, brain injuries, multiple trauma, chronic pain, and spinal cord injuries. Paradigm's database of more than 8,000 cases highlights best practices in hopes of reducing costs and improving results for its clients. It claims to return workers to the job in 41% of cases, compared to the 8% national average. Customers include state worker's comp funds, private insurers, and self-funded companies.Paradigm Management company was founded in 1991.

Uroplasty makes implants used primarily to treat urinary incontinence and overactive bladder. Its flagship product is Macroplastique, a soft-tissue bulking material for the treatment of urinary incontinence, that is injected during a minimally invasive outpatient procedure. Another minimally invasive device, the Urgent PC, uses electrical pulses to treat overactive bladder symptoms. Uroplasty's I-Stop Mid-Urethral Sling treats female incontinence. The company also sells soft-tissue bulking agents used in plastic surgery, vocal cord rehabilitation, and treatment of fecal incontinence. Uroplasty markets its products primarily in Europe and the US; it won FDA approval to market Macroplastique in 2006.

Focusing on orthopedics, wound care, and endoscopy, the firm makes products to repair joints, skin, soft tissue, and bone. Smith & Nephew plc orthopedics division makes hip, knee, and shoulder replacements, in addition to fixation and bone-growth devices used to repair broken bones. Smith & Nephew also makes arthroscopes, blades, digital cameras, and other surgical products through its endoscopy division. Its advanced wound management division manufactures and sells bandages and dressings used to treat a variety of injuries. The company operates in more than 30 countries worldwide.

DEKA Research and Development is perhaps best known for its founder and president Dean Kamen -- and for the Segway Personal Transporter he invented. DEKA is a design and engineering firm that develops innovative technologies, many of them in the field of medical devices. The Segway itself was an offshoot of the iBOT, an all-terrain, stair-climbing wheelchair the company developed with Independence Technology, a unit of Johnson & Johnson. (Kamen founded a separate company in 1999 to market the Segway.) DEKA's other products include a portable dialysis machine developed in partnership with Baxter International and an improved intravascular stent made with J&J's Cordis. DEKA was founded in 1982.

Methodist Hospital (also known as Methodist Hospital System) owns and operates several Houston-area medical centers, including the main Methodist Hospital in Houston and the suburban San Jacinto Methodist, Methodist Sugar Land, and Methodist Willowbrook hospitals. The flagship Methodist Hospital has 950 beds and is known for innovations in urology and neurosurgery, among other specialties. The hospital has educational and research affiliations with Cornell University's Weil Cornell Medical College, the New York-Presbyterian Hospital, and other organizations. The system also manages the Methodist Hospital Physician Organization and receives funding from the Methodist Hospital Foundation.

TearLab (formerly OccuLogix) can read your tears. TearLab diagnostics company has developed and commercialized the TearLab Osmolarity System, a tear collection and analysis system for use at the point of care. The system detects biomarkers that indicate ophthalmic conditions; its first testing product aids in the diagnosis of dry eye disease (DED). After several failed attempts to develop medical therapies for ophthalmic ailments including glaucoma and macular degeneration,TearLab company became focused on diagnostic testing; it changed its name to TearLab in 2010.

Bard Access Systems is all about giving doctors an all-access pass. The C. R. Bard division makes vascular access products such as dialysis catheters and central lines, as well as feeding tubes and equipment to inject contrast media for use with its ultrasound systems. It also provides ports, introducers, guidewires, and related accessories. The catheters are used to deliver chemotherapy, antibiotics, nutrition, and other products directly to the circulatory or other bodily systems. Bard Access Systems' products are sold under brands including Equistream, PowerPICC, PowerPort, and Site-Rite. The company also offers online clinical training to teach clinicians how to use their products.

Navilyst Medical is charting a new course for itself in the world of vascular disease. Formerly part of Boston Scientific, Navilyst Medical was spun off, acquired by private equity firm Avista Capital Partners in February 2008, and given a new name. The medical device maker will continue to market its two main fluid management and vascular access products to cardiologists, oncologists, and radiologists around the world. Its NAMIC kits, which account for about 60% of revenue, are used to manage fluids during cardiac catheterization procedures. Its Pressure Activated Safety Valves (PASV) account for the remaining 40% and are used to administer drugs during such procedures as chemotherapy.

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