Nationwide Children's Hospital (formerly Columbus Children's Hospital) in Columbus, Ohio, is one of the largest pediatric care centers in the US. The hospital has some 350 licensed beds and offers services in areas such as behavioral health, cardiology, hospice, orthopedics, and surgery. It has more than 850 health care providers on its medical staff and its emergency department treats more than 75,000 patients each year. The hospital also operates outpatient and specialty clinics in the area and a research institute which is investigating gene therapy. Nationwide Children's Hospital opened its doors in 1892 with nine beds.

EmCare works well under pressure. EmCare company is the largest provider of contracted emergency department staffing and management to more than 400 hospitals in 40 states. EmCare manages emergency services for hospitals, including recruiting and hiring medical directors, doctors, and nurses and monitoring their performance. The company is expanding its hospitalist services -- staffing hospitals with acute-care specialists. Emcare also provides anesthesiology services to surgery centers and teleradiology services to smaller regional hospitals. Other services include such administrative functions as billing, record keeping, and staff scheduling. EmCare is a subsidiary of Emergency Medical Services.

Genesis HealthCare is owned by a group of private equity investors from Formation Capital and the private equity arm of real estate investment firm J. E. Roberts. Genesis HealthCare Corporation cares for people when care is what counts. The company operates about 200 assisted living and skilled nursing facilities in more than a dozen states throughout the eastern US. Its facilities have some 25,000 beds total. Genesis HealthCare's rehabilitation division provides speech, physical, and occupational therapy services through contracts with health care providers. The company also offers respiratory therapy, adult day care, Alzheimer's care, dialysis, and home and hospice care.

CardioNet, Inc. provides ambulatory, continuous, and real-time outpatient management solutions for monitoring relevant and timely clinical information regarding an individual's health in the United States. It focuses on diagnosing and monitoring cardiac arrhythmias or heart rhythm disorders. The company offers Mobile Cardiac Outpatient Telemetry (MCOT) device that incorporates a patient-worn sensor attached to leads, which captures electrocardiogram (ECG) data and communicates wirelessly with a compact monitor that analyzes incoming information by applying proprietary algorithms designed to detect arrhythmias and eliminate data noise. Its MCOT device automatically transmits the ECG data to the CardioNet Monitoring Center, when the monitor detects an arrhythmic event. CardioNet also provides event monitoring services to record and store approximately 540 seconds of ECG signal; Holter monitoring services that store an image of the electrical impulses of every heartbeat or irregularity in either digital format on an internal compact flashcard or in analog format on a standard cassette tape located inside the monitor. In addition, it offers pacemaker monitoring services. CardioNet, Inc. markets its arrhythmia monitoring solutions, including the MCOT, primarily to cardiologists and electrophysiologists. CardioNet, Inc. has a strategic alliance with MedApps, Inc. CardioNet, Inc. was incorporated in 1994 and is headquartered in Conshohocken, Pennsylvania.

Sacred Heart Health System serves residents of Northwestern Florida, primarily through the Sacred Heart Hospital of Pensacola. The 460-bed acute care medical center includes the Sacred Heart Children's Hospital, the Sacred Heart Women's Hospital, and the Sacred Heart Regional Heart and Vascular Institute. Sacred Heart Hospital of Pensacola also specializes in trauma care, heart disease, cancer care, weight loss, stroke care, neurology, and orthopedics, and it has an educational affiliation with Florida State University College of Medicine. Sacred Heart Health System operates additional acute, long-term, primary, and specialty care centers in the region.

Organogenesis has the skinny on replacement tissue. Flagship product Apligraf is a human skin substitute approved to treat diabetic foot ulcers and venous leg ulcers caused by poor circulation. Rejection-resistant Apligraf is bio-engineered using living skin cells and has been used to treat chronic open wounds in some 250,000 patients; the company is developing a next-generation version of the material (using its VCT technology) using all human components. In addition to Apligraf, Organogenesis offers a line of biomaterials used in a range of surgical procedures to seal or reconstruct soft tissue, and it also develops regenerative technologies in the area of cosmetic skin rejuvenation.

United Surgical Partners International (USPI) brings together surgeons from across the US and the UK. The company owns or manages about 165 short-stay ambulatory surgery centers and surgical hospitals in the US and another four in the UK. The company creates centers from scratch, converts outpatient departments into stand-alone jointly run locations, and purchases existing facilities; contract management services are also available. USPI markets its facilities to patients, physicians, and insurance companies by touting their quality of care, convenience, and efficiency. Health care investment firm Welsh, Carson, Anderson & Stowe owns USPI.

Philips Healthcare makes it easier to get a look on the inside of things. Its parent company, Royal Philips Electronics, developed the first X-ray tube for medical use in 1918. Today, Philips Healthcare is a top global maker of medical imaging equipment, including X-ray, ultrasound, MR (magnetic resonance), and CT (computed tomography) scanners. The firm also makes patient monitors, resuscitation products, and data management systems, and it offers consulting, financing, training, and maintenance services. Philips Healthcare accounts for about 30% of its parent's sales and has operations in more than 60 countries.

Zila is developing and commercializing oral cancer detection technology, as well as equipment used to prevent and treat periodontal disease. Its lead cancer diagnostic product is the ViziLite Plus test kit, which uses a chemiluminescent light source to detect cancerous oral lesions. Despite its FDA approval as an adjunctive diagnostic (to be used along with other methods), the ViziLite has yet to fully take off in the US. Other products include the periodontal scalers, probes, fluoride rinses, and cleaning equipment for office and home use. After experiencing financial difficulties, Zila was acquired by private drugmaker TOLMAR Holding in 2009.

Health Plan of Nevada, a subsidiary of UnitedHealth, is a Nevada health maintenance organization (HMO) offering health care coverage to the state's residents. Its offerings include various HMO and point-of-service (POS) plans, as well as prescription drug coverage. It also gives members access to its affiliated multi-specialty medical group, Southwest Medical Associates, and other health care and wellness services. Established in 1982, Health Plan of Nevada offers plans through employer groups as well as to individuals. It sells its Senior Dimensions HMO plans to Medicare beneficiaries.

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