Commonwealth Health Corporation started out in 1926 as a 35-bed hospital. The holding company houses a full spectrum of health care facilities and services including The Medical Center, a 500-bed regional health care system comprised of three hospitals, long-term health care providers, and senior care, among other services. Commonwealth's outpatient offerings include nutrition therapy, a women's center, diabetes programs, and adult day care. The corporation's Center Care Health Benefits Program supplies employers with products and services to support the distribution and administration of employee benefits and healthcare services.

Radient Pharmaceuticals (formerly AMDL) is ready to hunt down cancer and some day might even be able to do something about it.Radient Pharmaceuticals company has developed and manufactures an in vitro blood test to detect over a dozen forms of cancer. Marketed as Onko-Sure, the test kits are approved for use in Europe and Asia; in the US the kits are approved for monitoring colorectal cancer, while in Canada it is used to detect lung cancer. Drug manufacturing facilities in China previously accounted for the bulk of the company's income, but it has chosen to focus its efforts on its Onko-Sure products. Other products in its pipeline include a technology with the potential to develop cancer vaccines.

Knoxville-based East Tennessee Children's Hospital (ETCH), with more than 150 beds, provides a full range of health care services to children from eastern Tennessee and nearby portions of Kentucky, North Carolina, and Virginia. Among its 90 specialized services are cardiology, neonatal care, orthopedics, and psychiatry. The hospital also offers several outside support services, including those for families of children stricken by cancer. Its emergency department treats some 70,000 patients each year. The hospital's roots are in the foundation of Knox County Crippled Children's Hospital in 1937, with less than 50 beds.

HFN offers a variety of managed care products and services for members throughout the Prairie State. The company provides health plans (PPO), long term care, and workers compensation insurance, as well as a Medicare Select product for seniors. HFN also offers an Internet-based claims repricing system for clients. HFN company opened its doors in 1985.

Hill-Rom's bottom line rests on hospital beds and other items for patient care and comfort. The company makes hospital beds, including beds for specific departments such as the ICU and OR, and other furnishings for patient rooms and home health use. It also provides non-invasive devices that improve circulation and treat bed sores -- both problems common to those confined to their beds. Hill-Rom sells its beds worldwide through a direct sales force and distributors; much of its revenue comes through deals with group purchasing organizations and government entities. The sole operating subsidiary of Hill-Rom Holdings, Hill-Rom also rents medical equipment, such as infusion pumps and ventilators.

Sheridan Healthcare is a physician practice management company. Sheridan Healthcare company manages the offices of anesthesiologists, neonatologists, pediatricians, radiologists, emergency room, and other general and specialty care physicians. The firm also provides such services as recruitment, billing, and administration. Sheridan Healthcare's major customers consist of hospitals and ambulatory surgical facilities. In addition, Sheridan manages group practices providing health care services for women, including obstetrics, gynecology, and midwifery, as well as pain management. Sheridan Healthcare company provides services to some 100 facilities in about 20 states. Sheridan Healthcare is controlled by private equity firm Hellman & Friedman.

Synergy Health (formerly Synergy Healthcare) provides outsourced medical and surgical support services to hospitals, nursing homes, and other health care providers, primarily in the UK and the Netherlands. Its Healthcare Solutions division sells continence and wound care products, protective clothing, and infection control services. The company's surgical instrument decontamination and sterilization unit is a top provider of such services to the UK National Health Service. Synergy Health's Linen Management Services and Laboratory Services handle clean linens and lab testing, respectively. Its Isotron unit offers sterilization services for medical devices and supplies in Europe, Asia, and South Africa.

Microsulis Medical (named for the Celtic goddess of healing waters, Sulis) manufactures and develops equipment and treatments centering around gynecological, neurological, dermatological, and vascular applications of microwave technology. Its lead products facilitate microwave endometrial ablation (MEA), a less invasive surgical alternative to a hysterectomy, and microwave tubal occlusion (MTO), used to target specific tumors in liver, lung, and bone cancer patients. Microsulis' MEA products and procedures are approved for use in the UK and the US. Venture capital firm 3i Group is one of the firm's major investors.

Biotel Inc. (the Company) provides contract medical devices, software and research services primarily used by medical corporations to satisfy their various outsourcing needs. Biotel holds three operating subsidiaries consisting of Braemar, Inc., Braemar, Inc. Distribution Center, and Agility Centralized Research Services, Inc. Braemar and Agility sell their products, technology and services to medical companies seeking assistance with their various research, manufacturing and clinical research needs. Products designed and manufactured by the Company become components in the product lines of other medical corporations, while research services offered 24 hours per day 7 days per week are used to support the clinical trials of medical corporations. Braemar is the world's largest provider of patient-worn battery powered diagnostic cardiology devices. Braemar designs, manufactures and services diagnostic cardiology devices including 24- and 48-hour Holter recorders and 30-day cardiac ECG event recorders for use by other medical corporations in their product lines.

Orthovita develops and sells materials for physicians to use as bone substitutes in reconstruction and replacement procedures. The company's products are designed to mimic natural bone characteristics and harden quicker than other available products. Orthovita's VITOSS product line, used for the repair of spinal and pelvic bone defects, accounts for about 60% of the company's sales. Its CORTOSS bone augmentation material -- expected to eventually become Orthovita's lead product -- received North American marketing approval from the FDA in 2009. Orthovita company already sells CORTOSS, which is used to repair vertebral compression fractures, in the EU and Australia.

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