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Medtronic Sofamor Danek USA, Inc. Company Profile It takes backbone to be the one of the world's biggest makers of spinal implants, and Medtronic Sofamor Danek USA has some serious spine. The Medtronic subsidiary's products treat degenerative diseases, deformities, and spine and cranium trauma. It also develops minimally invasive surgical techniques and computer-assisted surgical instruments, and provides physicians and patients with information through websites such as iscoliosis.com, back.com, and necksurgery.com. Medtronic Sofamor Danek USA markets and distributes its products worldwide. Along with hospitals and physicians, the company has federal contracts with the U.S. Department of Veterans Affairs to supply medical equipment to some of its hospitals.

A leading maker of implantable biomedical devices, the company makes defibrillators and pacemakers that shock the heart to help it beat normally. Subsidiary Medtronic Sofamor Danek makes spinal implant devices, while Medtronic CardioVascular produces catheters, stents, valves, balloons, and surgical ablation technologies used to treat vascular and heart disease. The company's neuromodulation division makes nerve and brain stimulation and drug delivery systems. Medtronic also makes devices for diabetes; ear, nose, and throat (ENT) conditions; and emergency medicine.

Mekanika specializes in making devices for the treatment of spinal instability. The company's restablilization system is used for treating degenerative joint disease, as well as trauma to the spine joint. Mekanika was founded by Chairman and Chief Science Officer David Holmes. The company has an alliance with the University of Miami School of Medicine.

Mentor Corporation produces cosmetic surgery products including Memory Gel breast implants, Prevelle Silk tissue expanders, and facial implants. Additional products include the Byron line of ultrasonic liposuction systems that remove unwanted fat and a line of post-surgery clothing called Caromed. Its Mentor Solutions software helps busy plastic surgeons manage their practices. Mentor's products are sold through its international sales force; it has operations in the US, Europe, and Africa. Founded in 1969, Johnson & Johnson purchased the company in 2009.

Most syringes are designed to inject medication into blood vessels, but Mercator MedSystems' (formerly EndoBionics) MicroSyringe is designed to go inside blood vessels and inject medication outside the vessel wall, allowing for a more targeted application of medication that reduces the amount dispersed to areas where it is not needed. In addition to delivering traditional injectable drugs, it can deliver stem cells and gene therapies. The MicroSyringe, which was approved for use by the FDA in 2004, can be used to treat tumors and vascular, cardiac, and neurological diseases.

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