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The Humane Society of the United States (HSUS) is a watchdog for, well, watchdogs, along with all sorts of other domestic and wild animals. A leading animal protection organization, HSUS has more than 10.5 million human members and constituents. The Humane Society of the United States supports the work of local humane societies and implements a variety of investigative, educational, advocacy, and legislative programs to promote animal welfare. The Humane Society of the United States campaigns have addressed issues such as animal fighting, factory farming, the fur trade, and hunting practices. Most of its revenue comes from contributions and grants. An affiliate, Humane Society International, operates in other countries. HSUS was founded in 1954.

The Interfaith Alliance (TIA) cuts across all religions to find common ground for the common good. The not-for-profit fosters democratic values and tolerance for different religious beliefs. The Interfaith Alliance has more than 185,000 members in the US from some 75 different faiths. The Interfaith Alliance work to promote civic participation, freedom of religion, civility in public discourse, and political involvement through town hall meetings, publications, teach-ins, vigils, and lobbying. TIA also airs State of Belief, a weekly radio show that explores religious issues and conflicts. The Interfaith Alliance was founded in 1994 by a group of religious leaders of different denominations.

The Jane Goodall Institute (JGI) knows it's not all good in the monkey world. The not-for-profit organization is dedicated to supporting the welfare of chimpanzees and other primates through education and public awareness. The Jane Goodall Institute main goals are to conserve primate habitat; promote an understanding of the interrelatedness of humans, animals, and the environment; increase non-invasive research on chimps and other primates; and improve the general welfare of chimpanzees and other animals. JGI has about 40 offices in Africa, Asia, Europe, and North America, including about 10 for child and teen program Roots & Shoots. The Jane Goodall Institute was founded in 1977 by Dr. Jane Goodall and Princess Genevieve di San Faustino.

The Jewish Federations of North America (formerly the United Jewish Communities) works to better Jewish life across the globe. One of North America's leading not-for-profit organizations, the JFNA represents more than 150 Jewish federations and about 400 independent Jewish communities across the continent. The federation raises and distributes more than $3.5 billion annually for social welfare, social services, and educational needs in its effort to support Israel and Jews worldwide. The Jewish Federations of North America, Inc. changed its name from United Jewish Communities to The Jewish Federations of North America in 2009.

The Leukemia & Lymphoma Society (LLS) is the world's largest voluntary health organization dedicated to funding blood cancer research, education and patient services. The Leukemia & Lymphoma Society is dedicated to finding a cure for leukemia, lymphoma, myeloma, and Hodgkin's disease. The Leukemia & Lymphoma Society, Inc. has pledged more than $600 million for blood cancer research since it was established in 1949. The Leukemia & Lymphoma Society also provides education programs and publications for health professionals and support for patients and their families. The Leukemia & Lymphoma Society, Inc. has chapters throughout the US and Canada. Nearly all of the group's revenue comes from contributions made in response to its fund-raising campaigns.

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