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The Royal Mencap Society is dedicated to helping adults and children with learning disabilities. Royal Mencap Society offers information and support services in areas such as housing, education, employment, and leisure activities in England, Wales, and Northern Ireland. (Housing services are provided through the Golden Lane Housing charity.) Mencap also runs campaigns for better treatment and opportunities for the learning disabled. Along with a group of other parents, Judy Fryd, who had a learning disabled child, formed the National Association of Parents of Backward Children in 1946, which became the Royal Society for Mentally Handicapped Children and Adults, later shortened to Royal Mencap Society.

The Royal Society for the Prevention of Cruelty to Animals (RSPCA), founded in 1824, was the first animal protection organization in the world. Royal Society for the Prevention of Cruelty to Animals influence has spread far beyond the UK to the establishment of similar organizations, such as the ASPCA in the US and the RSPCA in Australia. Royal Society for the Prevention of Cruelty to Animals manages about 30 clinics and more than 50 animal centers, as well as a handful of wildlife centers. Royal Society for the Prevention of Cruelty to Animals has a network of nearly 200 branches in England and Wales that operate under the RSPCA banner. In addition to these operations, the group supports legislation and campaigns that focus on animal welfare issues. Queen Victoria became the first British monarch to serve as the society's royal patron in 1840.

The San Francisco Opera has mighty big lungs. San Francisco Opera Association is the nation's second largest and its Western Opera Theater is the only national opera touring group. In addition to presenting new and classic works at War Memorial Opera House, it offers the annual free Opera in the Park as well as education and apprenticeship programs for children and young professionals. Considered an innovator, San Francisco Opera Association pioneered the US use of "supertitles" (an English translation projected over the stage) and has commissioned operas based on plays (A Streetcar Named Desire), people (slain San Francisco city supervisor Harvey Milk), and books (Dead Man Walking, Dangerous Liaisons). San Francisco Opera Association was founded in 1923 by Gaetano Merola.

Sanctuary is fast becoming an industry leading social enterprise, helping to set standards across the entire sector. Sanctuary Group companies forge and sustain innovative partnerships with both public and private sector organisations and are committed to providing affordable housing and effective social care services or facilities. Sanctuary Housing builds and manages low-cost housing projects. Sanctuary Housing Association manages more than 70,000 homes UK-wide through a network of strategically placed offices. Sanctuary also operates nursing homes through subsidiary Sanctuary Care, and home care businesses through subsidiary Sanctuary Home Care. Sanctuary Scotland Housing Association, another wholly-owned subsidiary, provides housing services in the south and central regions of Scotland. Sanctuary Housing was established in 1969 and is run as an exempt charity.

Save the Children helps poor and malnourished children in a dozen US states and more than 100 countries in areas such as education, health care, food security, and economic development. The humanitarian organization also participates in international disaster relief efforts for children and their families. Save the Children spends 90% of its budget on program services, with the rest going toward administration and fundraising. Save the Children was founded in 1932, inspired by the international children's rights movement begun in the UK in 1919 by Eglantyne Jebb, founder of the British Save the Children Fund. Save the Children a member of the International Save the Children Alliance.

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