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NMT Medical company develops implantable devices that treat defects in the walls of the heart's chambers. Its CardioSEAL and STARFlex implants close up holes in the heart, a condition suffered primarily by children.NMT Medical company markets CardioSEAL and STARFlex in the US, Canada, and Europe. A third device, BioSTAR, is a bioabsorbable implant that also corrects heart defects; it has been approved in Canada and Europe. NMT Medical acquired the exclusive rights to CardioSEAL from InnerVentions, a licensee of Children's Hospital Boston.

Novation isn't reinventing the wheels of healthcare, just greasing them a little.Novation company offers management consulting and supply chain services to hospitals and other health care facilities. Novation is one of the largest health care supply chain management firms in the nation, serving tens of thousands of health care organizations. It procures medical equipment and supplies, pharmaceuticals, laboratory equipment, food, and other products needed to keep the nation's health care facilities running. Novation is an affiliate of health care alliances VHA and University HealthSystem Consortium (UHC). Novation company was founded in 1998.

NuVasive company makes and markets medical devices for the surgical treatment of spinal disorders. NuVasive's products are primarily used in spinal fusion surgeries. Its minimally disruptive Maximum Access Surgery (MAS) platform enables surgeons to access the spine from the side of the body instead of from the front or back, and helps them avoid hitting nerves. NuVasive also offers the mesh, plates, screws, and biological implants (including allograft tissue) used with its MAS system.NuVasive company sells its FDA-approved products through a network of exclusive independent sales agencies, as well as NuVasive employees who target specific regions.

Oculus isn't the name of an all-seeing ancient Latin god or superhero, though it does use super-agents in its fight against the evil super-bug MRSA. Oculus Innovative Sciences works with proprietary platform technology Microcyn, a super-oxidized water-based solution designed to safely (i.e., without any known side effects) eliminate a wide range of annoying pathogens (including MRSA) attempting to infect patients with open wounds. Aside from use in wound care, the solution has potential applications for use in disinfectants and sterilization, as well as respiratory, dermatology, veterinary, and dental markets. Oculus' products are primarily sold through partnerships with distributors.

Ophthalmic Imaging Systems makes digital imaging products for use in ophthalmology. Its WinStation product line is used by retinal specialists and ophthalmologists to diagnose and treat diseases of the retina, including age-related macular degeneration. While the WinStation systems focus on imaging the back of the eye, the company's Digital Slit Lamp Imager emphasizes front-of-the-eye imaging. Ophthalmic Imaging Systems also sells image archiving, medical records management, and practice management software. Israel-based MediVision Medical Imaging holds more than 50% of the company and markets its products abroad. In 2008 MediVision agreed to acquire all of the company in an all-stock transaction.

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