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De Novo Ventures was formed in 2000 by seasoned investors and experienced medical device entrepreneurs who sought to share the lessons learned from a history of successful investing and building successful companies. They believed that their unique combination of skills and perspectives could help entrepreneurs to build companies which would have significant clinical impact and generate superior returns. Seven years later, this belief continues to hold true, demonstrated by De Novo investment success in selected medical device and biotechnology companies.With $650 million under management, De Novo has made more than 40 investments in medical devices and biotechnology across three funds. De Novo invest in all stages of enterprise development and growth – from early stage to late stage. De Novo unique background of leading companies as entrepreneurs and operating executives from start to exit enables us to advise entrepreneurs and management teams over the full life cycle of the company.Eight exits have occurred in DNV I -- four IPOs: Favrille (NASDAQ: FVRL), Fox Hollow Technologies (NASDAQ: EVVV), Renovis (NASDAQ: RNVS), and SenoRx (NASDAQ: SENO) and four acquisitions: CryoVascular Systems (Boston Scientific), TriVascular (Boston Scientific), LuMend (Johnson and Johnson) and Microvention (Terumo). DNV II has had one exit to date – Hansen Medical (NASDAQ: HNSN).

Delphi Ventures was founded in 1988 and is based in Menlo Park, California. Delphi Ventures is a venture capital firm specializing in seed early stage, and PIPE investments. The firm seeks to invest in healthcare companies with a focus on medical devices and biotechnology. Within medical devices, it invests in cardiovascular medicine, orthopedics, gynecology, minimally invasive surgery, urology, neurovascular medicine, and next-generation diagnostics. Within biotechnology, the firm typically invests after a company has either generated early human clinical data or completed preclinical efficacy and toxicity studies. It prefers to invest in companies that are discovering new ways to treat life-threatening diseases and designing new devices to make surgery less traumatic and treatments more precise. The firm primarily invests between $500,000 million and $12 million.

Delta Capital was founded by Don Mundie in 1992. Delta Capital makes venture capital investments in Alabama, Arkansas, Mississippi, Louisiana, and Tennessee. Delta Capital company invests in mostly early and expansion-stage companies in industries including health care, information and industrial technology, supply chain logistics, business services, and energy technology. It manages some $90 million in assets on behalf of institutional and high net worth individuals. Some of its investments include enterprise software provider Metatomix, and medical diagnostics company Atherotech.

Derbyshire First Investments Limited was founded in 1987 as the Derbyshire Enterprise Board Limited by the Derbyshire County Council. DFI is a joint owner with the Derby City Council of the Rosehill Business Centre, a small business incubator located in Derby. Derbyshire First Investments (DFI) provides business counseling and consulting to start-up and early-stage businesses. DFI company's investments typically range from £50,000 to £250,000 and are usually used to provide working capital, expenditure on capital equipment, refinance bank debt, or develop and market new products. DFI's investment activities are centered in Derby but extend to surrounding counties.

DeSilva & Phillips, LLC has completed nearly 200 transactions since it was founded by managing partners Roland DeSilva and Reed Phillips III in 1996. DeSilva & Phillips wants a piece of the media frenzy. The specialty investment banking firm offers advice and expertise about mergers, acquisitions, and strategy; corporate finance; business and property valuations; restructuring; and related services to clients in the media and communications industries. DeSilva & Phillips caters to customers including those involved in consumer and trade magazine publishing, trade show production, medical publishing, and digital media and technology.

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