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MultiCell Technologies is working on multiple therapeutics, but still sells liver cells on the side to help pay the rent. It is developing drug candidates to treat degenerative neurological diseases. Its MCT-125 candidate is being developed as a treatment for the fatigue that comes with multiple sclerosis while MCT-175 is intended to slow the progression of the disease. Two other candidates are targeting breast and cervical cancers. MultiCell also produces liver cells (hepatocytes) and a serum-free culture medium for research. Larger firms, including Corning and Pfizer, have licensed the company's liver cell lines.

Nanosphere is offering molecular diagnostics for the masses: Its molecular testing system is intended for use in hospital-based laboratories that don't have the money or expertise to maintain the complex genomic testing equipment often reserved for reference labs and research centers. Known as Verigene, the company's diagnostic system is a more compact and simpler workstation designed to perform multiple genomic and protein tests simultaneously on a single sample. The company also sells Verigene-compatible tests, including hematology, cystic fibrosis, and influenza diagnostic assays. Nanosphere has several other tests, including HPV (the virus that causes cervical cancer) in the works.

Nephros, Inc., a medical device company, engages in developing and marketing filtration products for therapeutic applications, infection control, and water purification. It primarily develops hemodiafiltration (HDF) products and technologies for treating patients with end stage renal disease (ESRD). The company also offers OLpur HD 190 high-flux dialyzer cartridge for use with hemodialysis or HDF machines. It has three products in various stages of development in HDF modality to deliver therapy to ESRD patients, which include OLpur MDHDF filter series consisting of MD190 and MD220 diafilters for HDF therapy; OLpur H2H, an add-on module designed to allow the common types of hemodialysis machines to be used for HDF therapy; and OLpur NS2000 system, a stand-alone HDF machine and associated filter technology. In addition, the company also develops dual stage ultrafilter water filtration system. It markets its products primarily to healthcare providers, such as hospitals, dialysis clinics, managed care organizations, and nephrology physician groups. The company was founded in 1997 and is headquartered in River Edge, New Jersey.

NeuroMetrix, Inc., a medical device company, engages in the development and marketing of products that aid physicians in the assessment and treatment of diseases and injuries of peripheral nerves, and provide regional anesthesia and pain control. The company provides ADVANCE NCS/EMG system, a platform for the performance of traditional nerve conduction studies and invasive electromyography procedures; NC-stat System, a point-of-service neurodiagnostic solution for the performance of nerve conduction studies; and consumables and accessories for use with its neurodiagnostic equipment. The company is also developing the ASCEND platform, a proprietary neuro-electrical guidance system; NM101, for use in chronic spinal cord injury; and Andara Oscillating Frequency Stimulation device that is designed as a single use implant to enhance neurological recovery in patients with devastating loss of movement and sensation from acute spinal cord injuries. The company offers NC-stat System primarily to primary care and internal medicine physicians; and ADVANCE NCS/EMG System to neurologists, physical medicine and rehabilitation physicians, neurosurgeons, orthopedic and hand surgeons, and pain medicine physicians. It sells its products directly to physician offices, clinics, and hospitals in the United States and internationally. The company has a strategic alliance with Cyberkinetics. NeuroMetrix, Inc. was founded in 1996 and is headquartered in Waltham, Massachusetts.

New Splint brings some much-needed stability to orthopedic surgery patients.New Splint company is a supplier of orthopedic implants and surgical instruments, distributing products manufactured by companies such as Jarit, Stille, and Waldemar LINK, and providing customers with custom-made products as well. Its products are used in primary and revision surgical procedures on the spine, hands, and feet. Established in 1989, New Splint is now a part of the medical and scientific products division of Dublin, Ireland-based United Drug plc, which acquired it in 2002.

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